He was attached with Advaita Ashrama (Kolkata) an English publication center of the Ramakrishna order for twelve years.
He was initiated by Srimat Swami Vireswaranandaji Maharaj and bestowed with Sanyasa in 1986 by Srimat Swami Gambhiranandaji Maharaj.
Before coming to the US, he served well-known educational institutions of the Ramakrishna Mission in Purulia, West-Bengal, Port Blair, Andaman Islands (Founder Secreary) and Narottam Nagar, Tirap, Arunachal Pradesh (Principal cum Secretary).
He has rendered his services at time of natural calamities in deep interiors of Assam, West Bengal, and Orissa.
In March 2013, Swami Ishatmananda was assigned to Vivekananda Vedanta Society of Chicago .
Under his leadership the society observed 150th Birth Anniversary of Swami Vivekananda through different programs held from August through November 2013.
He is also the Religious Adviser at the University of Chicago.
Apart from discoursing on various topics, he also conducts spiritual retreats and attends various programs across the United States at the invitation of devotees and other organizations.
He has written many articles that have been published in Ramakrishna Mission journals and other journals as well. He has given discourses on the Bhagavad Gita , extensively traveled different places of India, attended seminars and delivered lectures at colleges, universities, and devotee congregation on spiritual ideals and ideologies.
Advaita Ashram, Kolkata has published his discourses on the Bhagavad Gita as a set of 14 DVDs. Swami Ishatmananda has translated Swami Budhananda’s book “The mind and its control” to Bengali.